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CD34(+) progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rg(null) mice

Combining natural killer (NK) cell adoptive transfer with tumor-sensitizing chemotherapy is an attractive approach against recurrent ovarian cancer (OC), as OC is sensitive to NK cell-mediated immunity. Previously, we showed that CD34(+) hematopoietic progenitor cell (HPC)-derived NK cells can kill...

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Detalles Bibliográficos
Autores principales: Van der Meer, Jolien M.R., de Jonge, Paul K.J.D., van der Waart, Anniek B., Geerlings, Alexander C., Moonen, Jurgen P., Brummelman, Jolanda, de Klein, Janne, Vermeulen, Malou C., Maas, Ralph J.A., Schaap, Nicolaas P.M., Hoogstad-van Evert, Janneke S., Ottevanger, Petronella B., Jansen, Joop H., Hobo, Willemijn, Dolstra, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489932/
https://www.ncbi.nlm.nih.gov/pubmed/34616589
http://dx.doi.org/10.1080/2162402X.2021.1981049