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Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance

Chronic morphine intake for treating various pain is frequently concomitant with morphine-induced hyperalgesia and tolerance. The mechanisms can be explained by the activation of p38-MAPK proteins in microglia in the spinal cord horn. Exercise has been shown to prevent the development of microglia o...

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Detalles Bibliográficos
Autores principales: Gong, Xingrui, Fan, Rongmei, Zhu, Qinghong, Ye, Xihong, Chen, Yongmei, Zhang, Mazhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490029/
https://www.ncbi.nlm.nih.gov/pubmed/34616845
http://dx.doi.org/10.1155/2021/6667474