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Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance
Chronic morphine intake for treating various pain is frequently concomitant with morphine-induced hyperalgesia and tolerance. The mechanisms can be explained by the activation of p38-MAPK proteins in microglia in the spinal cord horn. Exercise has been shown to prevent the development of microglia o...
Autores principales: | Gong, Xingrui, Fan, Rongmei, Zhu, Qinghong, Ye, Xihong, Chen, Yongmei, Zhang, Mazhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490029/ https://www.ncbi.nlm.nih.gov/pubmed/34616845 http://dx.doi.org/10.1155/2021/6667474 |
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