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Evaluation of the Influence of Zhenwu Tang on the Pharmacokinetics of Digoxin in Rats Using HPLC-MS/MS

Digoxin (DIG) is a positive inotropic drug with a narrow therapeutic window that is used in the clinic for heart failure. The active efflux transporter of DIG, P-glycoprotein (P-gp), mediates DIG absorption and excretion in rats and humans. Up to date, several studies have shown that the ginger and...

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Detalles Bibliográficos
Autores principales: Li, Chao, Liang, Dahu, Liu, Yanhao, Shen, Chaozhuang, Wang, Xiaohu, Yang, Bin, Li, Xianghong, Wang, Weijia, Xu, Maodi, Pu, Zhichen, Hu, Hua, Wu, Zijing, Xie, Haitang, Sun, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490036/
https://www.ncbi.nlm.nih.gov/pubmed/34616474
http://dx.doi.org/10.1155/2021/2673183