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Evaluation of the Influence of Zhenwu Tang on the Pharmacokinetics of Digoxin in Rats Using HPLC-MS/MS
Digoxin (DIG) is a positive inotropic drug with a narrow therapeutic window that is used in the clinic for heart failure. The active efflux transporter of DIG, P-glycoprotein (P-gp), mediates DIG absorption and excretion in rats and humans. Up to date, several studies have shown that the ginger and...
Autores principales: | Li, Chao, Liang, Dahu, Liu, Yanhao, Shen, Chaozhuang, Wang, Xiaohu, Yang, Bin, Li, Xianghong, Wang, Weijia, Xu, Maodi, Pu, Zhichen, Hu, Hua, Wu, Zijing, Xie, Haitang, Sun, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490036/ https://www.ncbi.nlm.nih.gov/pubmed/34616474 http://dx.doi.org/10.1155/2021/2673183 |
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