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Release of HMGB1 in Podocytes Exacerbates Lipopolysaccharide-Induced Acute Kidney Injury

OBJECTIVE: Acute kidney injury (AKI) usually occurs during sepsis. Inflammation factors, such as high-mobility group box 1 (HMGB1), are dramatically upregulated under septic conditions. In our current work, the functions of HMGB1 in AKI were explored. METHODS: An AKI model was induced by the lipopol...

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Detalles Bibliográficos
Autores principales: Gao, Zhao, Lu, Li, Chen, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490059/
https://www.ncbi.nlm.nih.gov/pubmed/34616232
http://dx.doi.org/10.1155/2021/5220226