Effective gene expression prediction from sequence by integrating long-range interactions

How noncoding DNA determines gene expression in different cell types is a major unsolved problem, and critical downstream applications in human genetics depend on improved solutions. Here, we report substantially improved gene expression prediction accuracy from DNA sequences through the use of a de...

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Detalles Bibliográficos
Autores principales: Avsec, Žiga, Agarwal, Vikram, Visentin, Daniel, Ledsam, Joseph R., Grabska-Barwinska, Agnieszka, Taylor, Kyle R., Assael, Yannis, Jumper, John, Kohli, Pushmeet, Kelley, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490152/
https://www.ncbi.nlm.nih.gov/pubmed/34608324
http://dx.doi.org/10.1038/s41592-021-01252-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490152/
https://www.ncbi.nlm.nih.gov/pubmed/34608324
http://dx.doi.org/10.1038/s41592-021-01252-x

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