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High‐fat diet prevents the development of autoimmune diabetes in NOD mice

AIMS: Type 1 diabetes (T1D) has a strong genetic predisposition and requires an environmental trigger to initiate the beta‐cell autoimmune destruction. The rate of childhood obesity has risen in parallel to the proportion of T1D, suggesting high‐fat diet (HFD)/obesity as potential environmental trig...

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Detalles Bibliográficos
Autores principales: Clark, Amy L., Yan, Zihan, Chen, Sophia X., Shi, Victoria, Kulkarni, Devesha H., Diwan, Abhinav, Remedi, Maria S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490276/
https://www.ncbi.nlm.nih.gov/pubmed/34212475
http://dx.doi.org/10.1111/dom.14486