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Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections

The persistent increase of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) infections negatively impacts Tuberculosis treatment outcomes. Host-directed therapies (HDT) pose an complementing strategy, particularly since Mtb is highly successful in evading host-defense by manipulating host-...

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Detalles Bibliográficos
Autores principales: Heemskerk, M. T., Korbee, C. J., Esselink, J. J., dos Santos, C. Carvalho, van Veen, S., Gordijn, I. F., Vrieling, F., Walburg, K. V., Engele, C. G., Dijkman, K., Wilson, L., Verreck, F. A. W., Ottenhoff, T. H. M., Haks, M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490354/
https://www.ncbi.nlm.nih.gov/pubmed/34608194
http://dx.doi.org/10.1038/s41598-021-98980-z