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Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections
The persistent increase of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) infections negatively impacts Tuberculosis treatment outcomes. Host-directed therapies (HDT) pose an complementing strategy, particularly since Mtb is highly successful in evading host-defense by manipulating host-...
Autores principales: | Heemskerk, M. T., Korbee, C. J., Esselink, J. J., dos Santos, C. Carvalho, van Veen, S., Gordijn, I. F., Vrieling, F., Walburg, K. V., Engele, C. G., Dijkman, K., Wilson, L., Verreck, F. A. W., Ottenhoff, T. H. M., Haks, M. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490354/ https://www.ncbi.nlm.nih.gov/pubmed/34608194 http://dx.doi.org/10.1038/s41598-021-98980-z |
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