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A novel method for liquid-phase extraction of cell-free DNA for detection of circulating tumor DNA

Low yields of extracted cell-free DNA (cfDNA) from plasma limit continued development of liquid biopsy in cancer, especially in early-stage cancer diagnostics and cancer screening applications. We investigate a novel liquid-phase-based DNA isolation method that utilizes aqueous two-phase systems to...

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Detalles Bibliográficos
Autores principales: Janku, Filip, Huang, Helen J., Pereira, David Y., Kobayashi, Masae, Chiu, Chung Hei, Call, S. Greg, Woodbury, Kristen T., Chao, Felix, Marshak, Daniel R., Chiu, Ricky Y. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490367/
https://www.ncbi.nlm.nih.gov/pubmed/34608196
http://dx.doi.org/10.1038/s41598-021-98815-x