Contribution of p53 in sensitivity to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

The emergence of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) with activating EGFR mutations is a major hindrance to treatment. We investigated the effects of p53 in primary sensitivity and acquired resistance to EGFR-T...

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Detalles Bibliográficos
Autores principales: Jung, Sangyong, Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Park, Hyojeong, Lee, Hyeonjeong, Choi, Chang-Min, Sung, Young Hoon, Lee, Jae Cheol, Rho, Jin Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490392/
https://www.ncbi.nlm.nih.gov/pubmed/34608255
http://dx.doi.org/10.1038/s41598-021-99267-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490392/
https://www.ncbi.nlm.nih.gov/pubmed/34608255
http://dx.doi.org/10.1038/s41598-021-99267-z

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