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Contribution of p53 in sensitivity to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

The emergence of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) with activating EGFR mutations is a major hindrance to treatment. We investigated the effects of p53 in primary sensitivity and acquired resistance to EGFR-T...

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Detalles Bibliográficos
Autores principales:	Jung, Sangyong, Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Park, Hyojeong, Lee, Hyeonjeong, Choi, Chang-Min, Sung, Young Hoon, Lee, Jae Cheol, Rho, Jin Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490392/ https://www.ncbi.nlm.nih.gov/pubmed/34608255 http://dx.doi.org/10.1038/s41598-021-99267-z

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