Leu-to-Phe substitution at prM(146) decreases the growth ability of Zika virus and partially reduces its pathogenicity in mice

Zika virus (ZIKV) is a mosquito-borne flavivirus that causes febrile illness. The recent spread of ZIKV from Asia to the Americas via the Pacific region has revealed unprecedented features of ZIKV, including transplacental congenital infection causing microcephaly. Amino acid changes have been hypot...

Descripción completa

Detalles Bibliográficos
Autores principales: Inagaki, Takuya, Taniguchi, Satoshi, Kawai, Yasuhiro, Maeki, Takahiro, Nakayama, Eri, Tajima, Shigeru, Takeyama, Haruko, Lim, Chang Kweng, Saijo, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490429/
https://www.ncbi.nlm.nih.gov/pubmed/34608212
http://dx.doi.org/10.1038/s41598-021-99086-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490429/
https://www.ncbi.nlm.nih.gov/pubmed/34608212
http://dx.doi.org/10.1038/s41598-021-99086-2

Ejemplares similares