A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of hyperbranched polypeptides

A great hurdle in the production of synthetic polypeptides lies in the access of N-carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe, and protection of side-chain functional groups. Here we report a robust method for preparing unprotected NCA monomers in air and u...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Zi-You, Zhang, Zhengchu, Wang, Shuo, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490447/
https://www.ncbi.nlm.nih.gov/pubmed/34608139
http://dx.doi.org/10.1038/s41467-021-25689-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490447/
https://www.ncbi.nlm.nih.gov/pubmed/34608139
http://dx.doi.org/10.1038/s41467-021-25689-y

Ejemplares similares