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Dramatic increase in lever-pressing activity in rats after training on the progressive ratio schedule of cocaine self-administration

Transition from the highest rate of lever-pressing activity during the unloading (extinction) phase of a cocaine self-administration session to an extremely low activity rate during the remission phase is in many cases gradual. This makes it difficult to assess the duration of the unloading phase af...

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Detalles Bibliográficos
Autores principales: Tsibulsky, Vladimir L., Norman, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490463/
https://www.ncbi.nlm.nih.gov/pubmed/34608176
http://dx.doi.org/10.1038/s41598-021-98313-0