Cargando…

Medication effects on developmental sterol biosynthesis

Cholesterol is essential for normal brain function and development. Genetic disruptions of sterol biosynthesis result in intellectual and developmental disabilities. Developing neurons synthesize their own cholesterol, and disruption of this process can occur by both genetic and chemical mechanisms....

Descripción completa

Detalles Bibliográficos
Autores principales: Korade, Zeljka, Heffer, Marija, Mirnics, Károly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490477/
https://www.ncbi.nlm.nih.gov/pubmed/33820938
http://dx.doi.org/10.1038/s41380-021-01074-5