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Tissue factor cytoplasmic domain exacerbates post-infarct left ventricular remodeling via orchestrating cardiac inflammation and angiogenesis

The coagulation protein tissue factor (TF) regulates inflammation and angiogenesis via its cytoplasmic domain in infection, cancer and diabetes. While TF is highly abundant in the heart and is implicated in cardiac pathology, the contribution of its cytoplasmic domain to post-infarct myocardial inju...

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Detalles Bibliográficos
Autores principales: Chong, Suet Yen, Zharkova, Olga, Yatim, Siti Maryam J.M., Wang, Xiaoyuan, Lim, Xiong Chang, Huang, Chenyuan, Tan, Chia Yee, Jiang, Jianming, Ye, Lei, Tan, Michelle Siying, Angeli, Veronique, Versteeg, Henri H., Dewerchin, Mieke, Carmeliet, Peter, Lam, Carolyn S.P., Chan, Mark Y., de Kleijn, Dominique P.V., Wang, Jiong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490508/
https://www.ncbi.nlm.nih.gov/pubmed/34646369
http://dx.doi.org/10.7150/thno.63354