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Tumor microenvironment-based screening repurposes drugs targeting cancer stem cells and cancer-associated fibroblasts

The tumorous niche may drive the plasticity of heterogeneity and cancer stemness, leading to drug resistance and metastasis, which is the main reason of treatment failure in most cancer patients. The aim of this study was to establish a tumor microenvironment (TME)-based screening to identify drugs...

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Detalles Bibliográficos
Autores principales: Lee, Pei-Jung, Ho, Chao-Chi, Ho, Hao, Chen, Wan-Jiun, Lin, Chiu-Hua, Lai, Yi-Hua, Juan, Yi-Chen, Chu, Wen-Chung, Lee, Jia-Hua, Su, Sheng-Fang, Chen, Hsuan-Yu, Chen, Jeremy J. W., Chang, Gee-Chen, Li, Ker-Chau, Yang, Pan-Chyr, Chen, Huei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490509/
https://www.ncbi.nlm.nih.gov/pubmed/34646392
http://dx.doi.org/10.7150/thno.62676