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Lysyl hydroxylase 1 (LH1) deficiency promotes angiotensin II (Ang II)-induced dissecting abdominal aortic aneurysm

Rationale: The progressive disruption of extracellular matrix (ECM) proteins, particularly early elastin fragmentation followed by abnormalities in collagen fibril organization, are key pathological processes that contribute to dissecting abdominal aortic aneurysm (AAA) pathogenesis. Lysyl hydroxyla...

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Detalles Bibliográficos
Autores principales: Li, Hao, Xu, Haochen, Wen, Hongyan, Wang, Hongyue, Zhao, Ranxu, Sun, Yingying, Bai, Congxia, Ping, Jiedan, Song, Li, Luo, Mingyao, Chen, Jingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490513/
https://www.ncbi.nlm.nih.gov/pubmed/34646388
http://dx.doi.org/10.7150/thno.65277