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The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis

Rationale: Regulatory T cells (Treg cells) play an important role in maintaining peripheral tolerance by suppressing over-activation of effector T cells. The kinase PDK1 plays a pivotal role in conventional T cell development. However, whether PDK1 signaling affects the homeostasis and function of T...

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Detalles Bibliográficos
Autores principales: Feng, Peiran, Yang, Quanli, Luo, Liang, Sun, Yadong, Lv, Wenkai, Wan, Shuo, Guan, Zerong, Xiao, Zhiqiang, Liu, Feng, Li, Zehua, Dong, Zhongjun, Yang, Meixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490516/
https://www.ncbi.nlm.nih.gov/pubmed/34646383
http://dx.doi.org/10.7150/thno.63992