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Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study

Hypoxia caused by ischemia induces acidosis and neuroexcitotoxicity, resulting in neuronal death in the central nervous system (CNS). Monoacylglycerol lipase (MAGL) is a modulator of 2-arachidonoylglycerol (2-AG), which is involved in retrograde inhibition of glutamate release in the endocannabinoid...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tomoteru, Hatori, Akiko, Zhang, Yiding, Mori, Wakana, Kurihara, Yusuke, Ogawa, Masanao, Wakizaka, Hidekatsu, Rong, Jian, Wang, Lu, Liang, Steven, Zhang, Ming-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490517/
https://www.ncbi.nlm.nih.gov/pubmed/34646382
http://dx.doi.org/10.7150/thno.64320