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Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study
Hypoxia caused by ischemia induces acidosis and neuroexcitotoxicity, resulting in neuronal death in the central nervous system (CNS). Monoacylglycerol lipase (MAGL) is a modulator of 2-arachidonoylglycerol (2-AG), which is involved in retrograde inhibition of glutamate release in the endocannabinoid...
Autores principales: | Yamasaki, Tomoteru, Hatori, Akiko, Zhang, Yiding, Mori, Wakana, Kurihara, Yusuke, Ogawa, Masanao, Wakizaka, Hidekatsu, Rong, Jian, Wang, Lu, Liang, Steven, Zhang, Ming-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490517/ https://www.ncbi.nlm.nih.gov/pubmed/34646382 http://dx.doi.org/10.7150/thno.64320 |
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