IRGM/Irgm1 facilitates macrophage apoptosis through ROS generation and MAPK signal transduction: Irgm1(+/-) mice display increases atherosclerotic plaque stability

Rationale: Atherosclerosis plaque rupture (PR) is the pathological basis and chief culprit of most acute cardiovascular events and death. Given the complex and important role of macrophage apoptosis and autophagy in affecting plaque stability, an important unanswered question include is whether, and...

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Detalles Bibliográficos
Autores principales: Fang, Shaohong, Sun, Song, Cai, Hengxuan, Zou, Xiaoyi, Wang, Shanjie, Hao, Xinran, Wan, Xin, Tian, Jiangtian, Li, Zhaoying, He, Zhongze, Huang, Wei, Liang, Chenchen, Zhang, Zhenming, Yang, Liming, Tian, Jinwei, Yu, Bo, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490524/
https://www.ncbi.nlm.nih.gov/pubmed/34646375
http://dx.doi.org/10.7150/thno.62797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490524/
https://www.ncbi.nlm.nih.gov/pubmed/34646375
http://dx.doi.org/10.7150/thno.62797

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