MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility

PURPOSE: MTHFR, one of the major enzymes in the folate cycle, is known to acquire single-nucleotide polymorphisms that significantly reduce its activity, resulting in an increase in circulating homocysteine. Methylation processes are of crucial importance in gametogenesis, involved in the regulation...

Descripción completa

Detalles Bibliográficos
Autores principales: Ménézo, Yves, Patrizio, Pasquale, Alvarez, Silvia, Amar, Edouard, Brack, Michel, Brami, Charles, Chouteau, Jacques, Clement, Arthur, Clement, Patrice, Cohen, Marc, Cornet, Dominique, Dale, Brian, D’ Amato, Guiseppe, Jacquesson-Fournols, Laetitia, Mares, Pierre, Neveux, Paul, Sage, Jean Clement, Servy, Edouard, Huong, To Minh, Viot, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490548/
https://www.ncbi.nlm.nih.gov/pubmed/33914208
http://dx.doi.org/10.1007/s10815-021-02200-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490548/
https://www.ncbi.nlm.nih.gov/pubmed/33914208
http://dx.doi.org/10.1007/s10815-021-02200-6

Ejemplares similares