MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility

PURPOSE: MTHFR, one of the major enzymes in the folate cycle, is known to acquire single-nucleotide polymorphisms that significantly reduce its activity, resulting in an increase in circulating homocysteine. Methylation processes are of crucial importance in gametogenesis, involved in the regulation...

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Detalles Bibliográficos
Autores principales: Ménézo, Yves, Patrizio, Pasquale, Alvarez, Silvia, Amar, Edouard, Brack, Michel, Brami, Charles, Chouteau, Jacques, Clement, Arthur, Clement, Patrice, Cohen, Marc, Cornet, Dominique, Dale, Brian, D’ Amato, Guiseppe, Jacquesson-Fournols, Laetitia, Mares, Pierre, Neveux, Paul, Sage, Jean Clement, Servy, Edouard, Huong, To Minh, Viot, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490548/
https://www.ncbi.nlm.nih.gov/pubmed/33914208
http://dx.doi.org/10.1007/s10815-021-02200-6

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