CyTOF-Enabled Analysis Identifies Class-Switched B Cells as the Main Lymphocyte Subset Associated With Disease Relapse in Children With Idiopathic Nephrotic Syndrome

B cell depleting therapies permit immunosuppressive drug withdrawal and maintain remission in patients with frequently relapsing nephrotic syndrome (FRNS) or steroid–dependent nephrotic syndrome (SDNS), but lack of biomarkers for treatment failure. Post-depletion immune cell reconstitution may ident...

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Detalles Bibliográficos
Autores principales: Fribourg, Miguel, Cioni, Michela, Ghiggeri, GianMarco, Cantarelli, Chiara, Leventhal, Jeremy S., Budge, Kelly, Bin, Sofia, Riella, Leonardo V., Colucci, Manuela, Vivarelli, Marina, Angeletti, Andrea, Perin, Laura, Cravedi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490633/
https://www.ncbi.nlm.nih.gov/pubmed/34621271
http://dx.doi.org/10.3389/fimmu.2021.726428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490633/
https://www.ncbi.nlm.nih.gov/pubmed/34621271
http://dx.doi.org/10.3389/fimmu.2021.726428

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