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CyTOF-Enabled Analysis Identifies Class-Switched B Cells as the Main Lymphocyte Subset Associated With Disease Relapse in Children With Idiopathic Nephrotic Syndrome
B cell depleting therapies permit immunosuppressive drug withdrawal and maintain remission in patients with frequently relapsing nephrotic syndrome (FRNS) or steroid–dependent nephrotic syndrome (SDNS), but lack of biomarkers for treatment failure. Post-depletion immune cell reconstitution may ident...
Autores principales: | Fribourg, Miguel, Cioni, Michela, Ghiggeri, GianMarco, Cantarelli, Chiara, Leventhal, Jeremy S., Budge, Kelly, Bin, Sofia, Riella, Leonardo V., Colucci, Manuela, Vivarelli, Marina, Angeletti, Andrea, Perin, Laura, Cravedi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490633/ https://www.ncbi.nlm.nih.gov/pubmed/34621271 http://dx.doi.org/10.3389/fimmu.2021.726428 |
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