TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis Models

Podocyte injury and the appearance of proteinuria are key features of several progressive kidney diseases. Genetic deletion or selective inhibition of TRPC5 channels with small-molecule inhibitors protects podocytes in rodent models of kidney disease, but less is known about the human relevance and...

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Detalles Bibliográficos
Autores principales: Zhou, Yiming, Kim, Choah, Pablo, Juan Lorenzo B., Zhang, Fan, Jung, Ji Yong, Xiao, Li, Bazua-Valenti, Silvana, Emani, Maheswarareddy, Hopkins, Corey R., Weins, Astrid, Greka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490698/
https://www.ncbi.nlm.nih.gov/pubmed/34621762
http://dx.doi.org/10.3389/fmed.2021.721865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490698/
https://www.ncbi.nlm.nih.gov/pubmed/34621762
http://dx.doi.org/10.3389/fmed.2021.721865

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