Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes

The cohesin complex plays critical roles in genomic stability and gene expression through effects on 3D architecture. Cohesin core subunit genes are mutated across a wide cross-section of cancers, but not in germinal center (GC) derived lymphomas. In spite of this, haploinsufficiency of cohesin ATPa...

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Detalles Bibliográficos
Autores principales: Rivas, Martin A., Durmaz, Ceyda, Kloetgen, Andreas, Chin, Cristopher R., Chen, Zhengming, Bhinder, Bhavneet, Koren, Amnon, Viny, Aaron D., Scharer, Christopher D., Boss, Jeremy M., Elemento, Olivier, Mason, Christopher E., Melnick, Ari M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490713/
https://www.ncbi.nlm.nih.gov/pubmed/34621263
http://dx.doi.org/10.3389/fimmu.2021.688493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490713/
https://www.ncbi.nlm.nih.gov/pubmed/34621263
http://dx.doi.org/10.3389/fimmu.2021.688493

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