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A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids

BACKGROUND: Implantation metastasis is the main means of dissemination in ovarian cancer. Our previous studies showed that SET and MYND domain-containing protein 3 (SMYD3) expression was higher in ovarian cancer spheroids than in monolayers. SMYD3 enhancement of spheroid invasion and adhesion is med...

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Detalles Bibliográficos
Autores principales: Jiang, Yahui, Zhou, Tianyu, Shi, Yiwen, Feng, Weiwei, Lyu, Tianjiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490739/
https://www.ncbi.nlm.nih.gov/pubmed/34621667
http://dx.doi.org/10.3389/fonc.2021.690618