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The Role of Hydrophobic Nodes in the Dynamics of Class A β-Lactamases
Class A β-lactamases are known for being able to rapidly gain broad spectrum catalytic efficiency against most β-lactamase inhibitor combinations as a result of elusively minor point mutations. The evolution in class A β-lactamases occurs through optimisation of their dynamic phenotypes at different...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490755/ https://www.ncbi.nlm.nih.gov/pubmed/34621251 http://dx.doi.org/10.3389/fmicb.2021.720991 |