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The Role of Hydrophobic Nodes in the Dynamics of Class A β-Lactamases

Class A β-lactamases are known for being able to rapidly gain broad spectrum catalytic efficiency against most β-lactamase inhibitor combinations as a result of elusively minor point mutations. The evolution in class A β-lactamases occurs through optimisation of their dynamic phenotypes at different...

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Detalles Bibliográficos
Autores principales:	Olehnovics, Edgar, Yin, Junqi, Pérez, Adrià, De Fabritiis, Gianni, Bonomo, Robert A., Bhowmik, Debsindhu, Haider, Shozeb
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490755/ https://www.ncbi.nlm.nih.gov/pubmed/34621251 http://dx.doi.org/10.3389/fmicb.2021.720991

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