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Cochlear Sox2(+) Glial Cells Are Potent Progenitors for Spiral Ganglion Neuron Reprogramming Induced by Small Molecules
In the mammalian cochlea, spiral ganglion neurons (SGNs) relay the acoustic information to the central auditory circuits. Degeneration of SGNs is a major cause of sensorineural hearing loss and severely affects the effectiveness of cochlear implant therapy. Cochlear glial cells are able to form sphe...
Autores principales: | Chen, Zhen, Huang, Yuhang, Yu, Chaorong, Liu, Qing, Qiu, Cui, Wan, Guoqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490772/ https://www.ncbi.nlm.nih.gov/pubmed/34621745 http://dx.doi.org/10.3389/fcell.2021.728352 |
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