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Opa1 Prevents Apoptosis and Cisplatin-Induced Ototoxicity in Murine Cochleae
Optic atrophy1 (OPA1) is crucial for inner mitochondrial membrane (IMM) fusion and essential for maintaining crista structure and mitochondrial morphology. Optic atrophy and hearing impairment are the most prevalent clinical features associated with mutations in the OPA1 gene, but the function of OP...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490775/ https://www.ncbi.nlm.nih.gov/pubmed/34621753 http://dx.doi.org/10.3389/fcell.2021.744838 |