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Opa1 Prevents Apoptosis and Cisplatin-Induced Ototoxicity in Murine Cochleae

Optic atrophy1 (OPA1) is crucial for inner mitochondrial membrane (IMM) fusion and essential for maintaining crista structure and mitochondrial morphology. Optic atrophy and hearing impairment are the most prevalent clinical features associated with mutations in the OPA1 gene, but the function of OP...

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Detalles Bibliográficos
Autores principales: Dong, Tingting, Zhang, Xuejie, Liu, Yiqing, Xu, Shan, Chang, Haishuang, Chen, Fengqiu, Pan, Lulu, Hu, Shaoru, Wang, Min, Lu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490775/
https://www.ncbi.nlm.nih.gov/pubmed/34621753
http://dx.doi.org/10.3389/fcell.2021.744838