The Conformationally Sensitive Spatial Distance Between the TM3-4 Loop and Transmembrane Segment 7 in the Glutamate Transporter Revealed by Paired-Cysteine Mutagenesis

Excitatory amino acid transporters can maintain extracellular glutamate concentrations lower than neurotoxic levels by transferring neurotransmitters from the synaptic cleft into surrounding glial cells and neurons. Previous work regarding the structural studies of Glt(Ph), Glt(TK), excitatory amino...

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Detalles Bibliográficos
Autores principales: Qu, Qi, Wang, Ji, Li, Guiping, Chen, Rongqing, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490817/
https://www.ncbi.nlm.nih.gov/pubmed/34621751
http://dx.doi.org/10.3389/fcell.2021.737629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490817/
https://www.ncbi.nlm.nih.gov/pubmed/34621751
http://dx.doi.org/10.3389/fcell.2021.737629

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