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Alpk1 Sensitizes Pancreatic Beta Cells to Cytokine-Induced Apoptosis via Upregulating TNF-α Signaling Pathway

Pancreatic beta cell failure is the hallmark of type 1 diabetes (T1D). Recent studies have suggested that pathogen recognizing receptors (PRRs) are involved in the survival, proliferation and function of pancreatic beta cells. So far, little is known about the role of alpha-protein kinase 1 (ALPK1),...

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Detalles Bibliográficos
Autores principales: Ding, Fei, Luo, Xi, Tu, Yiting, Duan, Xianlan, Liu, Jia, Jia, Lijing, Zheng, Peilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490819/
https://www.ncbi.nlm.nih.gov/pubmed/34621265
http://dx.doi.org/10.3389/fimmu.2021.705751