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Alpk1 Sensitizes Pancreatic Beta Cells to Cytokine-Induced Apoptosis via Upregulating TNF-α Signaling Pathway
Pancreatic beta cell failure is the hallmark of type 1 diabetes (T1D). Recent studies have suggested that pathogen recognizing receptors (PRRs) are involved in the survival, proliferation and function of pancreatic beta cells. So far, little is known about the role of alpha-protein kinase 1 (ALPK1),...
Autores principales: | Ding, Fei, Luo, Xi, Tu, Yiting, Duan, Xianlan, Liu, Jia, Jia, Lijing, Zheng, Peilin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490819/ https://www.ncbi.nlm.nih.gov/pubmed/34621265 http://dx.doi.org/10.3389/fimmu.2021.705751 |
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