Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer

Tumors with elevated c-Myc expression often exhibit a highly aggressive phenotype, and c-Myc amplification has been shown to be frequent in esophageal cancer. Emerging data suggests that synthetic lethal interactions between c-Myc pathway activation and small molecules inhibition involved in cell cy...

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Detalles Bibliográficos
Autores principales: Hassan, Md Sazzad, Cwidak, Nicholas, Johnson, Chloe, Däster, Silvio, Eppenberger-Castori, Serenella, Awasthi, Niranjan, Li, Jun, Schwarz, Margaret A., von Holzen, Urs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490822/
https://www.ncbi.nlm.nih.gov/pubmed/34621175
http://dx.doi.org/10.3389/fphar.2021.746385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490822/
https://www.ncbi.nlm.nih.gov/pubmed/34621175
http://dx.doi.org/10.3389/fphar.2021.746385

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