Cargando…

Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Individuals with diabetes are exposed to a higher risk of perioperative stroke than non-diabetics mainly due to persistent hyperglycemia. LncRNA Meg3 has been considered as an important mediator in regulating ischemic stroke. However, the functional and regulatory roles of Meg3 in diabetic brain isc...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Cheng, Huang, Yan, Xia, Pingping, Zhang, Fan, Li, Longyan, Wang, E, Guo, Qulian, Ye, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490947/
https://www.ncbi.nlm.nih.gov/pubmed/34587716
http://dx.doi.org/10.4081/ejh.2021.3224