Cargando…

Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Individuals with diabetes are exposed to a higher risk of perioperative stroke than non-diabetics mainly due to persistent hyperglycemia. LncRNA Meg3 has been considered as an important mediator in regulating ischemic stroke. However, the functional and regulatory roles of Meg3 in diabetic brain isc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Cheng, Huang, Yan, Xia, Pingping, Zhang, Fan, Li, Longyan, Wang, E, Guo, Qulian, Ye, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications, Pavia, Italy 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490947/ https://www.ncbi.nlm.nih.gov/pubmed/34587716 http://dx.doi.org/10.4081/ejh.2021.3224

Ejemplares similares

Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis
por: Yuan, Yuan, et al.
Publicado: (2021)

Long noncoding RNA MALAT1 inhibits apoptosis induced by oxygen-glucose deprivation and reoxygenation in human brain microvascular endothelial cells
por: Xin, Jia-Wei, et al.
Publicado: (2017)

Hyperbaric oxygen protects HT22 cells and PC12 cells from damage caused by oxygen-glucose deprivation/reperfusion via the inhibition of Nrf2/System Xc-/GPX4 axis-mediated ferroptosis
por: Chen, Chunxia, et al.
Publicado: (2022)

Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis
por: Liu, Xing, et al.
Publicado: (2023)

Homocysteine induces ferroptosis in endothelial cells through the systemXc(−)/GPX4 signaling pathway
por: Shi, Jiahao, et al.
Publicado: (2023)

Long noncoding RNA ADAMTS9-AS1 represses ferroptosis of endometrial stromal cells by regulating the miR-6516-5p/GPX4 axis in endometriosis
por: Wan, Yiting, et al.
Publicado: (2022)

Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD
por: Zhang, Zixiao, et al.
Publicado: (2021)

MicroRNA-429/Cxcl1 Axis Protective Against Oxygen Glucose Deprivation/Reoxygenation-Induced Injury in Brain Microvascular Endothelial Cells
por: Leng, Jun, et al.
Publicado: (2020)

Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion
por: Sun, Zuo-Yan, et al.
Publicado: (2019)

Knockdown of RRM1 in tumor cells promotes radio-/chemotherapy induced ferroptosis by regulating p53 ubiquitination and p21-GPX4 signaling axis
por: Gao, Yang, et al.
Publicado: (2022)

Energy-Stress-Mediated AMPK Activation Promotes GPX4-Dependent Ferroptosis through the JAK2/STAT3/P53 Axis in Renal Cancer
por: Li, Yanze, et al.
Publicado: (2022)

Correction to: Homocysteine induces ferroptosis in endothelial cells through the systemXc−/GPX4 signaling pathway
por: Shi, Jiahao, et al.
Publicado: (2023)

Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis
por: Zhang, Qi, et al.
Publicado: (2022)

MDB-34. “INDUCING IRON IMBALANCE BY TARGETING THE ABCB7/GPX4 AXIS ACCELERATES FERROPTOSIS IN MEDULLOBLASTOMA”
por: Kanchan, Ranjana, et al.
Publicado: (2023)

Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition
por: Yi, Renxin, et al.
Publicado: (2020)

Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
por: Miao, Yu, et al.
Publicado: (2022)

Extracellular CIRP Promotes GPX4-Mediated Ferroptosis in Sepsis
por: Shimizu, Junji, et al.
Publicado: (2022)

Copper-dependent autophagic degradation of GPX4 drives ferroptosis
por: Xue, Qian, et al.
Publicado: (2023)

Novel circular RNAs expressed in brain microvascular endothelial cells after oxygen-glucose deprivation/recovery
por: Liu, Wei, et al.
Publicado: (2019)

iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4
por: Chen, Delin, et al.
Publicado: (2021)

GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma
por: Zhou, Yan, et al.
Publicado: (2022)

CREB stimulates GPX4 transcription to inhibit ferroptosis in lung adenocarcinoma
por: Wang, Zhixian, et al.
Publicado: (2021)

GPX4-independent ferroptosis—a new strategy in disease’s therapy
por: Ma, Tianyu, et al.
Publicado: (2022)

GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis
por: Wang, Qiujie, et al.
Publicado: (2021)

Lipid Peroxides Mediated Ferroptosis in Electromagnetic Pulse-Induced Hippocampal Neuronal Damage via Inhibition of GSH/GPX4 Axis
por: Lai, Yunfei, et al.
Publicado: (2022)

System X(c) (−)/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy
por: Li, Feng-Jiao, et al.
Publicado: (2022)

JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis
por: Lei, Shan, et al.
Publicado: (2022)

Mitophagy alleviates cisplatin-induced renal tubular epithelial cell ferroptosis through ROS/HO-1/GPX4 axis
por: Lin, Qisheng, et al.
Publicado: (2023)

Long Noncoding RNA MEG3 Interacts with p53 Protein and Regulates Partial p53 Target Genes in Hepatoma Cells
por: Zhu, Juanjuan, et al.
Publicado: (2015)

SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling
por: Zeng, Chong, et al.
Publicado: (2022)

Circ VRK1/microRNA-17/PTEN axis modulates the angiogenesis of human brain microvascular endothelial cells to affect injury induced by oxygen-glucose deprivation/reperfusion
por: Yang, Lei, et al.
Publicado: (2023)

FINO(2) Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation
por: Gaschler, Michael M., et al.
Publicado: (2018)

Glutathione peroxidase 4 (Gpx4) and ferroptosis: what's so special about it?
por: Conrad, Marcus, et al.
Publicado: (2015)

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis
por: Thayyullathil, Faisal, et al.
Publicado: (2021)

GPX4 Alleviates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting Ferroptosis
por: Xu, Wenchao, et al.
Publicado: (2022)

KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4
por: Zhao, Guangyin, et al.
Publicado: (2023)

Forsythoside A Mitigates Alzheimer's-like Pathology by Inhibiting Ferroptosis-mediated Neuroinflammation via Nrf2/GPX4 Axis Activation
por: Wang, Chunyue, et al.
Publicado: (2022)

Geniposide Possesses the Protective Effect on Myocardial Injury by Inhibiting Oxidative Stress and Ferroptosis via Activation of the Grsf1/GPx4 Axis
por: Shen, Yuehong, et al.
Publicado: (2022)

Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice
por: Zhao, Tianming, et al.
Publicado: (2022)

Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway
por: Jin, Xiaoming, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_56eoaau7efdor5o2mcbmm9nce7