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Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis
Individuals with diabetes are exposed to a higher risk of perioperative stroke than non-diabetics mainly due to persistent hyperglycemia. LncRNA Meg3 has been considered as an important mediator in regulating ischemic stroke. However, the functional and regulatory roles of Meg3 in diabetic brain isc...
Autores principales: | Chen, Cheng, Huang, Yan, Xia, Pingping, Zhang, Fan, Li, Longyan, Wang, E, Guo, Qulian, Ye, Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490947/ https://www.ncbi.nlm.nih.gov/pubmed/34587716 http://dx.doi.org/10.4081/ejh.2021.3224 |
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