Atractyloside Protect Mice Against Liver Steatosis by Activation of Autophagy via ANT-AMPK-mTORC1 Signaling Pathway

Objective: Adenine nucleotide translocase (ANT) can transport ADP from cytoplasm to mitochondrial matrix and provide raw materials for ATP synthesis by oxidative phosphorylation. Dysfunction of ANT leads to limitation of ADP transport and decrease of ATP production. Atractyloside (ATR) is considered...

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Detalles Bibliográficos
Autores principales: Zhang, Pengfei, Cheng, Xinyu, Sun, Huimin, Li, Yajing, Mei, Wuxuan, Zeng, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490973/
https://www.ncbi.nlm.nih.gov/pubmed/34621170
http://dx.doi.org/10.3389/fphar.2021.736655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490973/
https://www.ncbi.nlm.nih.gov/pubmed/34621170
http://dx.doi.org/10.3389/fphar.2021.736655

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