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piRNA‐ and siRNA‐mediated transcriptional repression in Drosophila, mice, and yeast: new insights and biodiversity

The PIWI‐interacting RNA (piRNA) pathway acts as a self‐defense mechanism against transposons to maintain germline genome integrity. Failures in the piRNA pathway cause DNA damage in the germline genome, disturbing inheritance of “correct” genetic information by the next generations and leading to i...

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Detalles Bibliográficos
Autores principales: Onishi, Ryo, Yamanaka, Soichiro, Siomi, Mikiko C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490990/
https://www.ncbi.nlm.nih.gov/pubmed/34347367
http://dx.doi.org/10.15252/embr.202153062