Targeting the JAK/STAT Pathway: A Combined Ligand- and Target-Based Approach

[Image: see text] Janus kinases (JAKs) are a family of proinflammatory enzymes able to mediate the immune responses and the inflammatory cascade by modulating multiple cytokine expressions as well as various growth factors. In the present study, the inhibition of the JAK–signal transducer and activa...

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Detalles Bibliográficos
Autores principales: Galvez-Llompart, Maria, Ocello, Riccardo, Rullo, Laura, Stamatakos, Serena, Alessandrini, Irene, Zanni, Riccardo, Tuñón, Iñaki, Cavalli, Andrea, Candeletti, Sanzio, Masetti, Matteo, Romualdi, Patrizia, Recanatini, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491162/
https://www.ncbi.nlm.nih.gov/pubmed/33998810
http://dx.doi.org/10.1021/acs.jcim.0c01468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491162/
https://www.ncbi.nlm.nih.gov/pubmed/33998810
http://dx.doi.org/10.1021/acs.jcim.0c01468

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