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Targeting the JAK/STAT Pathway: A Combined Ligand- and Target-Based Approach
[Image: see text] Janus kinases (JAKs) are a family of proinflammatory enzymes able to mediate the immune responses and the inflammatory cascade by modulating multiple cytokine expressions as well as various growth factors. In the present study, the inhibition of the JAK–signal transducer and activa...
Autores principales: | Galvez-Llompart, Maria, Ocello, Riccardo, Rullo, Laura, Stamatakos, Serena, Alessandrini, Irene, Zanni, Riccardo, Tuñón, Iñaki, Cavalli, Andrea, Candeletti, Sanzio, Masetti, Matteo, Romualdi, Patrizia, Recanatini, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491162/ https://www.ncbi.nlm.nih.gov/pubmed/33998810 http://dx.doi.org/10.1021/acs.jcim.0c01468 |
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