Insights on the structure–function relationship of human multidrug resistance protein 7 (MRP7/ABCC10) from molecular dynamics simulations and docking studies

ATP‐binding cassette (ABC) transporters superfamily mediates multidrug resistance in cancer by extruding structurally distinct chemotherapeutic agents, causing failure in chemotherapy. Among the 49 ABC transporters, multidrug resistance protein 7 (MRP7 or ABCC10) is relatively new and has been ident...

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Detalles Bibliográficos
Autores principales: Wang, Jing‐Quan, Cui, Qingbin, Lei, Zi‐Ning, Teng, Qiu‐Xu, Ji, Ning, Lin, Lusheng, Liu, Zhijun, Chen, Zhe‐Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491190/
https://www.ncbi.nlm.nih.gov/pubmed/34766143
http://dx.doi.org/10.1002/mco2.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491190/
https://www.ncbi.nlm.nih.gov/pubmed/34766143
http://dx.doi.org/10.1002/mco2.65

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