Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin‐resistant forms of obesity and type 2 diabetes mellitus

Diet‐induced obesity, the metabolic syndrome, type 2 diabetes (DIO/MetS/T2DM), and their adverse sequelae have reached pandemic levels. In mice, DIO/MetS/T2DM initiation involves diet‐dependent increases in lipids that activate hepatic atypical PKC (aPKC) and thereby increase lipogenic enzymes and p...

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Detalles Bibliográficos
Autores principales: Sajan, Mini P., Hansen, Barbara C., Acevedo‐Duncan, Mildred, Kindy, Mark S., Cooper, Denise R., Farese, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491214/
https://www.ncbi.nlm.nih.gov/pubmed/34766133
http://dx.doi.org/10.1002/mco2.54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491214/
https://www.ncbi.nlm.nih.gov/pubmed/34766133
http://dx.doi.org/10.1002/mco2.54

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