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Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes

Rationale: Preschool wheezing is heterogeneous, but the underlying mechanisms are poorly understood. Objectives: To investigate lower airway inflammation and infection in preschool children with different clinical diagnoses undergoing elective bronchoscopy and BAL. Methods: We recruited 136 children...

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Detalles Bibliográficos
Autores principales: Robinson, Polly F. M., Fontanella, Sara, Ananth, Sachin, Martin Alonso, Aldara, Cook, James, Kaya-de Vries, Daphne, Polo Silveira, Luisa, Gregory, Lisa, Lloyd, Clare, Fleming, Louise, Bush, Andrew, Custovic, Adnan, Saglani, Sejal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491264/
https://www.ncbi.nlm.nih.gov/pubmed/33961755
http://dx.doi.org/10.1164/rccm.202009-3696OC