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Synthesis, crystal structure and Hirshfeld surface analysis of 5-cyclo­propyl-N-(2-hy­droxy­eth­yl)-1-(4-methyl­phen­yl)-1H-1,2,3-triazole-4-carboxamide

The title compound, C(15)H(18)N(4)O(2), was obtained via a two-step synthesis (Dimroth reaction and amidation) for anti­cancer activity screening and was selected from a 1H-1,2,3-triazole-4-carboxamide library. The cyclo­propyl ring is oriented almost perpendicular to the benzene ring [dihedral angl...

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Detalles Bibliográficos
Autores principales: Pokhodylo, Nazariy T., Slyvka, Yurii, Pavlyuk, Volodymyr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491517/
https://www.ncbi.nlm.nih.gov/pubmed/34667635
http://dx.doi.org/10.1107/S2056989021009774