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Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors

[Image: see text] The emergence of a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents an urgent public health crisis. Without available targeted therapies, treatment options remain limited for COVID-19 patients. Using medicinal chemistry and rational drug desig...

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Detalles Bibliográficos
Autores principales: Huff, Sarah, Kummetha, Indrasena Reddy, Tiwari, Shashi Kant, Huante, Matthew B., Clark, Alex E., Wang, Shaobo, Bray, William, Smith, Davey, Carlin, Aaron F., Endsley, Mark, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491550/
https://www.ncbi.nlm.nih.gov/pubmed/34570513
http://dx.doi.org/10.1021/acs.jmedchem.1c00566